Bioprinting Revolution: The Power of Progressive Cavity Technology

Category: Blog,Expert's Corner
Aug 15, 2023

Bioprinting has experienced a significant revolution, driven by the groundbreaking progressive cavity pump technology. This innovative approach has redefined the precision and possibilities of bioprinting processes. At the forefront of this revolution are ViscoTec’s extrusion-based bioprinting printheads, known as product brand Puredyne® by ViscoTec. Leveraging the principles of progressive cavity pump technology, these printheads have taken bioprinting to new heights, offering process safety, repeatability, and simplicity. The Puredyne cap b5, specifically engineered for single-use applications, features a design that effectively minimizes dead space, therefore maximizing material utilization.

The significance of progressive cavity technology lies in its ability to accurately dispense materials and bioinks with varying viscosities, ranging from low to high. This versatility has revolutionized the field, enabling bioprinting across a wide spectrum of applications. Regardless of the material’s characteristics, researchers and scientists can now achieve impeccable print results, thanks to the precise application enabled by this technology.

One key advantage of the Puredyne printheads is their accuracy, boasting an impressive 99% precision rate when dispensing materials. This level of precision is critical in bioprinting, where the smallest variations can have a profound impact on the final product’s quality.

Moreover, the incorporation of an adjustable suck back function ensures precise start-stop points during the printing process, contributing to consistent line widths and high-resolution outputs. This feature enhances the reproducibility of prints, providing researchers with reliable results that can be easily replicated.

Beyond precision, the Puredyne printheads also prioritize user convenience. The compact design, accompanied by patented single-use caps, simplifies operation and ensures safety by preventing cross-contamination. With an integrated stepper motor, the printheads can seamlessly integrate into most existing 3D printers or bioprinters, making them accessible and user-friendly.

To complement the capabilities of the Puredyne printheads, ViscoTec has introduced the Puredyne® temperature control b5. This heating and cooling unit is a pivotal component in achieving successful bioprinting outcomes. It offers precise temperature control, which is crucial for maintaining optimal conditions necessary for cell viability throughout the entire printing process.

The Puredyne® temperature control b5’s modular design allows users to adjust the temperature within a range of 39 – 104 °F (4 – 40 °C), offering flexibility to strategically manipulate the flow behavior of the dosing media. This ensures a stable process with reproducible results, particularly when ambient temperatures undergo fluctuations.

Seamless integration between the heating and cooling unit and the Puredyne® cap b5 is achieved through a plug-in mechanism, forming a cohesive printing unit. The unit housing features a viewing slot that allows for effortless monitoring of the medium’s filling level.

Puredyne® Video

The thermal regulation of the medium is achieved using a solid-state thermoelectric Peltier element. By adjusting the temperature setpoint via the device, users can easily control the desired temperature. The unit is designed to direct airflow upwards with the assistance of an integrated miniature fan, preserving the integrity of the printed object beneath the print head by eliminating any interference.

In conclusion, Progressive Cavity Technology, in conjunction with the Puredyne® printheads and the Temperature Control b5, has ushered in a new era of bioprinting possibilities. Researchers in both academia and industry are now experiencing groundbreaking success in areas such as cancer research, organ modeling, cell scaffold construction, and personalized medicine development, with greater confidence and accuracy. The seamless integration of these technologies holds the potential to revolutionize medicine and various scientific disciplines, pushing the boundaries of scientific innovation.

Temperature control b5 Video

About the Author:

Annaliese Vojnich, Business Development Manager Puredyne® & Hygienic Solutions, ViscoTec America

Meet Annaliese Vojnich, a dynamic business development manager currently overseeing the Puredyne® brand and the Hygienic Solutions division for ViscoTec America. Annaliese’s professional journey spans various industries, including pharmaceuticals, medical technology, research and development, hygienic manufacturing, and sales, equipping her with a versatile skill set that stands at the forefront.

Earning a bachelor’s degree in Dietetics/Nutritional Sciences from the esteemed University of Georgia in 2018, Annaliese’s academic foundation underscores her commitment to knowledge and growth. Her pursuit of education extended further with a Certificate in Women’s Entrepreneurship from Cornell University, where she refined her leadership abilities in 2022.

Annaliese’s passion for biotechnology began in 2014 at the Center for Applied Genetic Technologies, a University of Georgia facility. During her time as an assistant lab manager and research assistant, her responsibilities were concentrated on genetic transformation, somatic embryogenesis, plant breeding and genetics, and tissue culture management.

Annaliese’s foundation has positioned her to excel not only in sales and management roles but also in bridging the gap between innovation and real-world applications. Her current role at ViscoTec America, where she contributes to cutting-edge dosing technology and bioprinting advancements, showcases her ability to merge her passion for science with her sales acumen.

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