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New Approach Methodologies: From Theory to Validation
New Approach Methodologies (NAMs) are redefining how preclinical safety and efficacy are evaluated by shifting away from traditional animal models toward human-relevant, technology-driven approaches...
Biomaterials Frontier
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Next-Gen 3D Printed Orthotics and Prosthetics
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Post-Processing : The Last Piece of Puzzle?
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The Latest...
Lattice Brief: FDA Clears First 3D-Printed Implant Made at the Point of Care
This week in healthcare 3D printing and 3D technologies: the FDA cleared the first 3D-printed implant made at a point-of-care institution, as Walter Reed's 3D Medical Applications Center and 3D...
Episode 122: New Approach Methodologies (NAMs) with Dr. Lowry Curley
Not long ago, growing a human brain in a lab was science fiction. Today, brain organoids can test drugs, model neurological diseases, and even play Pac-Man! 89% of drugs manufactured through animal...
FDA-Cleared 3D-Printed Titanium Spine Cages: Why Additive Manufacturing Is Becoming the Standard
Welcome to the Lattice Brief, 3DHEALS weekly newsletter. This week, Elevation Spine received 510(k) clearance for Saber-C AVIA, a zero-profile cervical fusion device built on a porous 3D-printed...
Episode 121: Absorbable Biomaterials with Dr. Rao Bezwada
Absorbable biomaterials have transformed modern medicine, enabling implants, sutures, and drug-delivery systems that safely degrade after completing their function. Dr. Rao S. Bezwada has helped...
Episode 119: Where Is Dental 3D Printing with Dr. Nabeel Cajee
Dentistry was one of the earliest healthcare fields to adopt 3D printing. Today, digital workflows touch everything from treatment planning and surgical guides to restorations and personalized...
What is Physical AI? - A Guide for Healthcare
Physical AI is artificial intelligence that can sense, reason, and act in the physical world through robots, devices, instruments, and automated systems. In healthcare, that means AI is no longer...
Expert's Corner
What is Physical AI? - A Guide for Healthcare
Physical AI is artificial intelligence that can sense, reason, and act in the physical world through robots, devices, instruments, and automated systems. In healthcare, that means AI is no longer limited to software that analyzes records or images; it is also showing up in surgical systems, rehabilitation platforms, wearables, smart medical devices, hospital robots, and automated laboratory infrastructure. There are several motivations behind writing this guide: 1. The increasing number of Pitch3D startups is now deploying physical AI to build or defend their existing products. 2. An increasing number of incumbent AI giants, including leading companies like NVIDIA, or venture capital firms, believe the next phase of AI-driven growth will be from this category of technologies. In part one of this guide, we focus on general concepts and players in current healthcare and life science sectors.
Is Chairside 3D-Printed Crown Finally a Reality?
For years, "print a crown while the patient waits" has been more aspiration than clinical routine. Milling has dominated same-day restorative dentistry, and resin-based 3D printing has largely been confined to models, surgical guides, and temporaries. That balance appears to be shifting in light of the latest news in dental 3D printing. Across the first half of 2026, a cluster of regulatory clearances, material launches, and academic results suggests that permanent, chairside-printed restorations are moving from novelty to a real clinical option. Why is this such a big deal? The current permanent crown workflow involves at least two office visits and a minimum of two weeks of waiting time for the crown to be ready for placement. During the weeks between visits, patients often have to wear a clunky, essentially nonfunctional temporary crown. With chairside permanent crown availability, patients can potentially receive same-day treatment, avoiding additional trips to the dentist and the inconveniences of a temporary crown. So it is a huge deal. However, after some investigation, there appear to be real caveats that any dentist or patient should understand before assuming printed crowns can simply replace milled or sintered ones.
Navigating 2025: What’s Ahead for Healthcare Venture Capital and Startups
It is already midsummer, but if you missed the latest numbers focusing on early-stage healthcare investing, here are some highlights that could be relevant to rising entrepreneurs and fundraising startups in the deep tech, medtech, and biopharma space. The first quarter of 2025 marked a pivotal moment for the venture capital and healthcare startup landscape. As uncertainty continued to ripple through global financial markets, investors, founders, and analysts closely monitored funding trends, exit prospects, and innovation hotspots. Drawing on the latest data from leading industry reports—including the HSBC Healthcare Annual Report Q1 2025, PitchBook-NVCA Venture Monitor, Carta’s VC Fund Performance Report, and Wilson Sonsini’s Entrepreneurs Report—we break down the most important takeaways for startups, investors, and ecosystem players. Please find the downloadable versions of these reports at the end of this summary "Reference" section.
AI in Healthcare 3D Printing: The Future is Now
The medical field is undergoing a revolutionary transformation, driven by two cutting-edge technologies: Artificial Intelligence (AI) and 3D printing. When these forces collide, they unleash unparalleled potential for innovation, personalization, and improved patient outcomes. From custom prosthetics to intricate organ models for surgical planning, the synergy between AI and 3D printing is reshaping healthcare as we know it. Let's delve into some of the latest advancements, drawing insights from pioneering researchers and practitioners at the forefront of this exciting intersection.
3D Printing in Post Mortem Reconstruction
3D printing and scanning technology has improved since its introduction in 1986, when the first stereolithographic (SLA) systems were introduced [1] and are embraced by both surgical and forensic departments across the world [2]. Despite the applications of 3D printed prosthetics in both medicine and various disciplines of forensic science to date, limited studies can be found on the use of the application in Forensic Medicine, specifically, during post mortem reconstruction. The aim of this article is to explore current reconstruction techniques in forensic medicine to improve aesthetics and bony structure stability in situations requiring repair of skull and facial bone damage due to trauma or the tissue retrieval process in post mortem procedures.
Five Powerful Books Every Entrepreneur Must Read to Win-2025
You must learn to think like a great investor to build a great company. The most successful entrepreneurs aren’t just skilled operators but master capital allocators, strategically investing their money, time, energy, and focus. In the early stages of a company, financial capital is often the least scarce resource; the real differentiators are insight, discipline, and the ability to place asymmetric bets on the future. Understanding the game of investing—whether in markets, people, or ideas—gives you a decisive edge in entrepreneurship. These five books have impacted my perception profoundly in 2024. They sharpen entrepreneurs' ability to think probabilistically, navigate uncertainty, endure discomfort/pain, and maximize their chances of success in a field where most remain blind to the underlying rules. If you are willing to read, you already belong to the most exclusive club in the world.
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