From Academia: Sonolithography, Single Cell Bioprinting, Melt Electrowriting

While FDM, SLA, two-photon laser, drop on demand are some of the most popular biofabrication methods, this “From Academia” issue includes three less well-known but trending methods that could be complementary or alternative to the typical 3D bioprinting process. The first article introduces a biofabrication method using ultrasound waves, also known as sonolithography. This gentle method can rapidly generate 2D cell patterns for a variety of materials, as well as act as a complementary technique to additive manufacturing where surface patterning combined with layer‐by‐layer fabrication can facilitate the generation of structures with more internal complexity. However, this method does not allow selectively targeting and manipulating individual cells. The second article addresses exactly that problem with a single cell bioprinting method using short laser pulses, which allow for the precise and efficient selection and positioning of individual mammalian cells, as well as transferring of specific cell/cells to a target surface with precision and high cell viability. The third publication was written in 2017, but we are anticipating the author’s upcoming paper in a few weeks. This paper reviews the principles behind a fabrication technique called melt eletrowriting (or electrostatic writing) and also compares it to an adjacent technique called electrospinning. The author also lists potential biomedical applications of this technique.

From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino ( if you want to share relevant academic publications with us.

Sonolithography: In‐Air Ultrasonic Particulate and Droplet Manipulation for Multiscale Surface Patterning

Authored by Jenna M. Shapiro  Bruce W. Drinkwater  Adam W. Perriman  Mike Fraser. Advanced Materials Technologies. December 2 2020

Single Cell Bioprinting with Ultrashort Laser Pulses

Authored by Jun Zhang  Patrick Byers  Amelie Erben  Christine Frank  Levin Schulte‐Spechtel  Michael Heymann  Denitsa Docheva  Heinz P. Huber  Stefanie Sudhop  Hauke Clausen‐Schaumann. Advanced Functional Materials. March 26 2021

Melt electrowriting with additive manufacturing principles

Authored by Paul D. Dalton. Current Opinion in Biomedical Engineering. June 2017

Optimizing Bioprinting Hydrogel using Machine Learning, Modified or Decellularized ECM

3D Bioprinting Substrate Stiffness – Often Overlooked, But Always at Work

Artificial Intelligence and 3D Printing

Synthetic and Natural Bioinks

From Academia: Tweaking Bioinks Palette, One-Drop 3D Printing

From Academia: Nanoclay Bioink, Machine Learning, Hydrogel Design Strategies for 3D Bioprinting

3D Bioprinting: The Yellow Brick Road of (Part 1)

From Academia: Tweaking Bioinks Palette, One-Drop 3D Printing