From Academia: 3D Printing Contact Lenses, Optics, and Visualization

In this issue of “From Academia“, we include four recent research publications related to “seeing”, including articles focusing on creating smart contact lenses, cornea, glass optics, and microscope leveraging 3D printing technologies. In the first article, researchers presented a way to develop hydrogel-based contact lenses that can have biosensing capabilities, including sensing eye blinking (peristaltic pressure), PH, and Na+ level, adding another tool to the future wearable market. In the second article, researchers demonstrated how additive manufacturing of gradient index (GRIN) silica-titania glass via direct ink writing method could potentially create a variety of conventional and unconventional optical functions in a flat glass component with no surface curvature. In the third article, the researchers described a way to create a 3D corneal stroma using an orthogonally oriented pure electro-compacted collagen (EC). The researchers believe this technique could potentially be used to create a future full-thickness corneal replacement. In the final article, the authors presented UC2 (You. See. Too.), a low-cost, 3D-printed, open-source, modular microscopy toolbox. The authors demonstrate its versatility by realizing a complete microscope development cycle from concept to experimental phase and developing an open standard in optics to facilitate interfacing with various complementary platforms. 

From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino (info@3dheals.com) if you want to share relevant academic publications with us.

Microengineered poly(HEMA) hydrogels for wearable contact lens biosensing

Authored by Yihang Chen, Shiming Zhang, Qingyu Cui, Jiahua Ni, Xiaochen Wang, Xuanbing Cheng, Halima Alem, Peyton Tebon, Chun Xu, Changliang Guo,  Rohollah Nasiri, Rosalia Moreddu, Ali K. Yetisen, Samad Ahadian, Nureddin Ashammakhi, Sam Emaminejad, Vadim Jucaud,   Mehmet R. Dokmeci  and  Ali Khademhosseini. Lab on a Chip. 13 October 2020

3D printed gradient index glass optics

Authored by Rebecca Dylla-Spears, Timothy D. Yee, Koroush Sasan, Du T. Nguyen, Nikola A. Dudukovic, Jason M. Ortega, Michael A. Johnson, Oscar D. Herrera, Frederick J. Ryerson and Lana L. Wong, Science Advances. 18 November 2020 

Biomimetic corneal stroma using electro-compacted collagen

Authored by Zhi Chen, Xiao Liu, Jingjing You, Yihui Song, Eva Tomaskovic-Crook, Gerard Sutton, Jeremy M.Crook, Gordon G.Wallace. Acta Biomaterialia, 1 September 2020 

A versatile and customizable low-cost 3D-printed open standard for microscopic imaging

Authored by Benedict Diederich, René Lachmann, Swen Carlstedt, Barbora Marsikova, Haoran Wang, Xavier Uwurukundo, Alexander S. Mosig & Rainer Heintzmann. Nature Communications. 25 November 2020

From Academia: Bioprinted Cancer Models, Microprinted Imaging Probe, 3DTech for Congenital Heart Disease

From Academia: 3D Printed Lens, Silk as Biomaterial, Aspiration-assisted freeform bioprinting

From Academia: 3D Bioprined Dendritic Vascular Networks, Cornea, Alternative Drug Delivery

Product Liability : Biocompatible Materials in 3D Printed Products

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