In this week’s issue of “From Academia”, we share three recent publications focusing on how to leverage 3D printing to improve drug delivery. The first article described a bilayer FDM 3D printed tablet that can release TB medication at two different PH, thereby potentially optimize drug potency and avoid drug interactions. The second publication describes a dual extrusion 3D printing process that can leverage different material compositions and geometries to create different drug release profiles. In the final article, researchers described a multifunctional bone graft as a drug delivery vehicle by incorporating the three primary soy isoflavones: genistein, daidzein, and glycitein onto a 3D printed (3DP) tricalcium phosphate (TCP) scaffold with designed pores, endowing them with in vitro chemopreventive, bone-cell proliferating, and immune-modulatory potential.
“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.
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Authored by Atabak Ghanizadeh Tabriz, Uttom Nandi, Andrew P. Hurt, Ho-Wah Hui, Shyam Karki, Yuchuan Gong, Sumit Kumar, Dennis Douroumis. International Journal of Pharmaceutics. January 2020
Authored by Witold Jamroz, Mateusz Kurek, Joanna Szafraniec-Szczesny, Anna Czech, Karolina Gawlak, Justyna Knapik-Kowalczuk, Bartosz Leszczynski, Andrzej Wrobel, Marian Paluch, Renata Jachowicz. Euoprean Journal of Pharmaceutrical Science. February 2020
Controlled release of soy isoflavones from multifunctional 3D printed bone tissue engineering scaffolds
Authored by Naboneeta Sarkar, Susmita Bose. Acta Biomaterialia. September 2020
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3DHEALS From Academia (Collective) – This section features recent, relevant, close to commercialization academic publications in the space of healthcare 3D printing, 3D bioprinting, and related emerging technologies.