In this issue of “From Academia”, we include two recent publications in the space of bioprinting and organ-on-a-chip. The first article presents one of the seminal work on cardiovascular bioprinting where the researchers demonstrated the design and development of functional macroscale model of a human heart. Other than the heart, the second article explores the fabrication of an immunocompetent in vitro gut model of the stomach. Here, researchers integrated a mucosal barrier, a three-dimensional ECM, resident and infiltrating immune cells, to simulate a functional crosstalk that ultimately triggers cellular processes representative of inflammation.

“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino (info@3dheals.com) if you want to share relevant academic publications with us.

In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid

Authored by Molly E. Kupfer, Wei-Han Lin, Vasanth Ravikumar, Kaiyan Qiu, Lu Wang, Ling Gao, Didarul B. Bhuiyan, Megan Lenz, Jeffrey Ai, Ryan R. Mahutga, DeWayne Townsend, Jianyi Zhang, Michael C. McAlpine, Elena G. Tolkacheva, Brenda M. Ogle. Circulation Research. 31 March 2020

Neutrophilic infiltration in organ-on-a-chip model of tissue inflammation

Authored by Nikolce Gjorevski, Blandine Avignon, Régine Gérard, Lauriane Cabon, Adrian B. Roth, Michael Bscheider, and Annie Moisan. Lab on a Chip. 6 August 2020

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