This “From Academia” issue highlights two recent publications exploring pre-clinical models in the world of bioprinted tissue constructs and an article demonstrating an in-vitro model for the study of neurogeneration. The first article explores the development of a of a novel bioink with tunable O2 release using a calcium peroxide source (CPO). The bioink was later tested to fabricate fibroblasts and cardiomyocytes and were shown with improved metabolic activity and viability under hypoxic condition. Focused more on a pre-clinical animal study, the second article explores a the development and implantation of bioprinted construct using adipose tissue-derived mesenchymal stem cells in rabbits, after three months, have shown successful cartilage and subchondral bone regeneration. The third article demonstrated the development of a cost-efficient and scalable 3D spheroid assay system to study neuroblast migration.

“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino (tino.rance@gmail.com) if you want to share relevant academic publications with us.

3D Bioprinting of Oxygenated Cell‐Laden Gelatin Methacryloyl Constructs

Authored by Ahmet Erdem, Mohammad Ali Darabi, Rohollah Nasiri, Sivakoti Sangabathuni, Yavuz Nuri Ertas, Halima Alem, Vahid Hosseini, Amir Shamloo, Ali S. Nasr, Samad Ahadian, Mehmet R. Dokmeci, Ali Khademhosseini, Nureddin Ashammakhi. Advanced Healthcare Materials, 5 August 2020

Osteochondral regeneration using scaffold-free constructs of adipose tissue-derived mesenchymal stem cells made by a bio three-dimensional printer with a needle-array in rabbits

Authored by Daiki Murata, Yoshihiro Kunitomi, Kaori Harada, Satoshi Tokunaga, Shoko Takao, Koichi Nakayama. Regenerative Therapy. 24 July 2020

A Semi-automated and Scalable 3D Spheroid Assay to Study Neuroblast Migration

Authored by Martin Ducker, Valerie Millar, Daniel Ebner, Francis G. Szele. Stem Cell Reports. 6 August 2020. 

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From Academia: 4D Printing, 3D Printing Fish Gelatin for Drug Delivery, and Simulating Nasal Cavities

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