This “From Academia” issue highlights two recent publications exploring pre-clinical models in the world of bioprinted tissue constructs and an article demonstrating an in-vitro model for the study of neurogeneration. The first article explores the development of a of a novel bioink with tunable O2 release using a calcium peroxide source (CPO). The bioink was later tested to fabricate fibroblasts and cardiomyocytes and were shown with improved metabolic activity and viability under hypoxic condition. Focused more on a pre-clinical animal study, the second article explores a the development and implantation of bioprinted construct using adipose tissue-derived mesenchymal stem cells in rabbits, after three months, have shown successful cartilage and subchondral bone regeneration. The third article demonstrated the development of a cost-efficient and scalable 3D spheroid assay system to study neuroblast migration.

“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino (tino.rance@gmail.com) if you want to share relevant academic publications with us.

3D Bioprinting of Oxygenated Cell‐Laden Gelatin Methacryloyl Constructs

Authored by Ahmet Erdem, Mohammad Ali Darabi, Rohollah Nasiri, Sivakoti Sangabathuni, Yavuz Nuri Ertas, Halima Alem, Vahid Hosseini, Amir Shamloo, Ali S. Nasr, Samad Ahadian, Mehmet R. Dokmeci, Ali Khademhosseini, Nureddin Ashammakhi. Advanced Healthcare Materials, 5 August 2020

Osteochondral regeneration using scaffold-free constructs of adipose tissue-derived mesenchymal stem cells made by a bio three-dimensional printer with a needle-array in rabbits

Authored by Daiki Murata, Yoshihiro Kunitomi, Kaori Harada, Satoshi Tokunaga, Shoko Takao, Koichi Nakayama. Regenerative Therapy. 24 July 2020

A Semi-automated and Scalable 3D Spheroid Assay to Study Neuroblast Migration

Authored by Martin Ducker, Valerie Millar, Daniel Ebner, Francis G. Szele. Stem Cell Reports. 6 August 2020. 

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In today’s issue, we share with you a collection of latest publications that explores a diverse take on digital imaging-modelling and 3D printing in Healthcare. Here, mixed reality (MR), augmented reality (AR), and virtual reality (VR) utilized for better simulation and visualization for pre-surgical and educational applications, and the combination of 3D printing technology with MR/AR/VR to further enchance modelling and simulation workflows as well as patient education. Stay tuned for a more in-depth discussion on the technical and clinical insights on our upcoming Expert Corner blog soon.

“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.

Email: Rance Tino (info@3dheals.com) if you want to share relevant academic publications with us.

Mixed Reality Combined With Three-Dimensional Printing Technology in Total Hip Arthroplasty: An Updated Review With a Preliminary Case Presentation

Authored by Peng-fei Lei, Shi-long Su, Ling-yu Kong, Cheng-gong Wang, Da Zhong, Yi-he Hu. Orthopaedic Surgery, October 2019

A Review of Simulation Applications in Temporal Bone Surgery

Authored by Tanisha S. Kashikar, Thomas F. Kerwin, Aaron C. Moberly, Gregory J. Wiet. Laryngoscope Investig Otolaryngol, 7 June 2019

Comparison of 3-Dimensional and Augmented Reality Kidney Models With Conventional Imaging Data in the Preoperative Assessment of Children With Wilms Tumors

Authored by Lianne M. Wellens, Jene Meulstee, Cornelis P. van de Ven. Quant Imaging Med Surg, 5 April 2019

Augmented Reality and Three-Dimensional Printing in Percutaneous Interventions on Pulmonary Arteries

Authored by Jan Witowski et al. Quant Imaging Med Surg, January 2019

Patient-specific 3D Printed and Augmented Reality Kidney and Prostate Cancer Models: Impact on Patient Education

Authored by Nicole Wake, Andrew B. Rosenkrantz, Richard Huang, Katalina U. Park, James S. Wysock, Samir S. Taneja, William C. Huang, Daniel K. Sodickson & Hersh Chandarana. 3D Printing in Medicine, 19 February 2019

Augmented Reality, Surgical Navigation, and 3D Printing for Transcanal Endoscopic Approach to the Petrous Apex

Authored by Samuel R. Barber, Kevin Wong, Vivek Kanumuri, Ruwan Kiringoda, Judith Kempfle, Aaron K. Remenscheider, Elliott D. Kozin, and Daniel J. Lee. OTO Open, 29 October 2018

Visualization Improves Supraclavicular Access to the Subclavian Vein in a Mixed Reality Simulator

Authored by Joshua Warren Sappenfield, William Brit Smith, Lou Ann Cooper, David Lizdas, Drew B. Gonsalves, Nikolaus, Gravenstein, Samsun Lampotang, Albert R. Robinson III. Anesthesia & Analgesia. July 2018

Neurosurgical Virtual Reality Simulation for Brain Tumor Using High-definition Computer Graphics: A Review of the Literature

Authored by Taichi Kin, Hirofumi Nakatomi, Kaoyuki Shono, Seiji Nomura, Toki Saito, Hiroshi Oyama, Nobuhito Saito. Neurologia medico-chirurgica. 15 October 2017

Augmented Reality in Computer-Assisted Interventions Based on Patient-Specific 3D Printed Reference

Authored by Rafael Moreta-Martinez, David Garcia-Mato, Monica Garcia-Sevilla, Ruben Perez-Mananes, Jose Calvo-Haro, Javier Pascau. Healthcare Technology Letters. September 2018

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