In this issue of “From Academia”, we share three articles focusing on maximizing bioinks palette using complementary thermo-reversible gelatin network, dual-factor releasing and gradient-structuring, and what one-drop 3D printing is. The first article addresses the limited availability of functional bioinks for bioprinting where they demonstrate the use of a thermo-reversible gelatin network to allow the printing of sophisticated biomaterials not attainable by standard printing parameters. The second article presents the ulitization of dual-factor releasing mesenchymal stem cell (MSC)–laden hydrogels and a biodegradable polymer to bioprint a viable anisotropic cartilage constructs. In-vitro and in-vivo studies were demonstrated to show tissue maturation and organization, which may be sufficient for translation to patients. The third article explores a novel resin 3D printing technology which continously fabricates a 3D structure with a single droplet of resin via the control of its three phase contact line (TCL).
“From Academia” features recent, relevant, close to commercialization academic publications. Subjects include but not limited to healthcare 3D printing, 3D bioprinting, and related emerging technologies.
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Authored by Liliang Ouyang, James P. K. Armstrong, Yiyang Lin, Jonathan P. Wojciechowski, Charlotte Lee-Reeves, Daniel Hachim, Kun Zhou, Jason A. Burdick, Molly M. Stevens. Science Advances. 18 September 2020
3D bioprinting dual-factor releasing and gradient-structured constructs ready to implant for anisotropic cartilage regeneration
Authored by Ye Sun, Yongqing You, Wenbo Jiang, Bo Wang, Qiang Wu, Kerong Dai. Science Advances. 9 September 2020.
Authored by Yu Zhang, Zhichao Dong, Chuxin Li, Huifeng Du, Nicholas X. Fang, Lei Wu & Yanlin Song. Nature Communications. 17 September 2020