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Description

Readily3D

We developed a rapid tomographic bioprinter to help biologists push the frontiers of biofabrication.

Headquarters Readily3D SA EPFL Innovation Park CH–1015 Lausanne Switzerland
Categories: Bioprinting /Biofabrication, Tissue Engineering
Website: readily3d.com
CEO: Damien Loterie Co-founder and CEO, B.Sc.,MBA Phone: +41 22 575 30 34
Links:

Details

Readily3D, a Switzerland-based volumetric 3D bioprinting startup, also an EPFL spin-out , developed Tomolite and Apparite to make research in biosciences quicker and more efficient. Founded in 2020, Readily3D originates from research work started in 2017 at Ecole Polytechnique Fédérale de Lausanne. Existing bioprinting technologies are slow, which tends to reduce cell viability. They also have a poor ability to produce complex anatomical structures, such as vasculatures. To overcome these limitations, we created Tomolite: a unique bioprinter, allowing biologists to print an entire cell-laden volume at once, in less than a minute and without impairing cell viability.

The company has taken the first step towards developing a 3D-printed living model of the human pancreas for testing diabetes medicines. Readily3D’s novel technology is being deployed within the EU-funded Enlight project and is reportedly capable of 3D printing a biological tissue containing human stem cells in just 30 seconds. As the project’s official bioprinter manufacturer, the company has adapted its proprietary contactless tomographic illumination technology to suit the specific needs of pancreatic tissue structures.

“Developing a system that can 3D print tissue at the cubic centimeter scale and faithfully replicates the functioning of a live pancreas is a huge challenge, which we hope to meet with this technology,” said Christophe Moser, Head of the EPFL’s Laboratory of Applied Photonics Devices (LAPD).

 

Technology:

Tomographic 3D printing rapidly solidifies photosensitive inks in three dimensions, using shaped light beams from multiple angles. As the entire build volume is illuminated simultaneously, centimeter-scale biological systems are produced in just a few seconds. After printing, the object is simply separated from the uncured ink and collected.

Our printing method is light-based, so it does not induce any shear stress on the printed cells. The remarkably low photoinitiator content (eg 1mg/mL LAP) and low light dose (<600 mJ/cm²) make tomographic bioprinting a cell-friendly technique.