3D Bioprinting Bone
Why is 3D bioprinting bone so important? Because the autologous bone graft is simply not enough. What many people perhaps don’t know is that bone harvesting is not only limited by donor sites and but also adding additional risk to surgeries. Just imagine patients with head and neck (or other) cancers, in addition to the wrath of cancer, they have to endure disfiguring but life-saving surgeries. Therefore, being able to use tissue engineering, digital design, 3D printing to create space-filling fully implantable bone tissue is many surgeons’ dream. However, what appears hard and homogenous, an ideal for 3D printing, is not easy, because the musculoskeletal system is actually a dynamic, ever-changing vascularized organ. Therefore, bioprinting bone faces many similar challenges to bioprinting other organ systems. In this webinar, we have included world-class scientists and entrepreneurs to share their latest discoveries and entrepreneurial journeys.
Brian is the manufacturing manager at EpiBone Inc, a biotech start-up seeking to transform skeletal repair. Since joining in 2015, Brian has progressed the development of EpiBone’s products and is now leading the Phase I/II clinical manufacturing of EpiBone’s tissue-engineered anatomical bone graft. Brian received his MS/BS in Biomedical Engineering from Pennsylvania State University.
Casper Slots has research experience in materials science and development, tissue engineering and drug delivery – all in the fields of 3D printing. He has spent the last five years developing new 3D printable biological inks and drug delivery systems. He is a registered nurse with clinical experience and has extensive experience working with materials scientists, as well as with patients, clinicians, and surgeons. Casper is the Chief Commercial Officer of Particle3D where he oversees the development and commercial strategies of the company. Casper holds an MSc (Eng.) in Health & Welfare Technology, a BSc in Nursing, and is a TEDx speaker.
Ibrahim Tarik Ozbolat is an Associate Professor of Engineering Science and Mechanics, Biomedical Engineering and Neurosurgery, and a member of the Huck Institutes of the Life Sciences at Penn State University. Dr. Ozbolat’s main area of research is in the field of 3D Bioprinting. He has been working on several aspects of bioprinting such as bioprinting processes, bioink materials, bioprinters and post-bioprinting tissue maturation for manufacturing of more than a dozen tissues and organs. Dr. Ozbolat is a leading scientist with over 140 publications, including a sole-authored book in his domain. Due to his notable contributions to the field of bioprinting, he has received several prestigious international and national awards including 2014 NSF CAREER Award, 2014 SME Outstanding Young Manufacturing Engineer Award, 2014 ASME Chao and Trigger Young Manufacturing Engineer Award, 2014 ASME Tau Pi Sigma Gold Medal, 2015 IIE Dr. Hamid K. Eldin Outstanding Early Career Industrial Engineer in Academia Award, 2015 International Outstanding Young Researcher in Freeform and Additive Manufacturing Award and 2017 Hartz Family Career Development Professorship at Penn State.
Dr. Caralynn Nowinski Collens is the CEO and co-founder of Dimension Inx, a regenerative biomaterials platform developing medical products that repair tissues and organs. She is passionate about building teams and organizations that harness technology to drive transformational change and improve the quality of people’s lives. Previously as the co-founder of UI LABS, a first-of-its-kind technology organization focused on the digital future of industries, Caralynn built the organization from concept in late 2011 through launch in 2014, serving as CEO until 2019. After starting her first company while a joint medical/business student at the University of Illinois at Chicago, Caralynn spent her early career in venture capital and corporate finance, primarily focused on technology-based university spin-outs. Caralynn is proud to have been a member of the Chicago Chapter of the Young Presidents’ Organization (YPO) and recognized as one of Crain’s Chicago Business’ “Forty Under Forty”, “Notable Women in Manufacturing”, and “Tech 50”.
Joe is currently a biomedical engineer and PhD Candidate at Mount Sinai, working in the labs of Drs.Kevin Costa and Junqian Xu, in addition to being the lead engineer with the Sinai BioDesign innovation team and helping run the MSIG and GRO-Biotech student groups. Previously, he worked at 3D Systemson technical development in the consumer marketing department and as a liaison with engineering project management teams, in addition to an earlier stint at experiential marketing firm Affinitive.
Joe received his bachelors in Biomedical Engineering from Macaulay Honors College at The City College of New York, where he also remains active in the Zahn Innovation Center, an on-campus tech startup incubator.He has also been involved in several startup ventures in the hardware and biotech spaces. Several years ago, Joe took Proto-Sauce, through NYCEDC’s Futureworks Incubator, with the goal of developing new materials for resin-based 3D printing. More recently, he had the privilege to serve as the CTO of BioSapien, using advanced manufacturing to create new devices for the treatment of cancer. Beyond Joe’s direct startup work, he has also continued to participate in Futureworks and other New York City startup programs as a mentor.