Medical

3D Printing for Veterinary Medicine

According to American Pet Product Association (APPA), the current pet-related product industry is worth more than 100 billion dollars, where one-third is veterinary-related products based on 2020 data. There is a steady growth of this remarkable industry, but there are definitely more pet owners now than ever after the pandemic. Some interesting veterinary-related data can be found here.

According to AVMA, Vets experienced a 50% increase in new pets per week Mar-Aug. 2020. Similar to human society, the pet market experiences similar supply chain and manufacturing challenges. Can 3D printing provide better, more efficient veterinary care and a more robust supply chain than the traditional way of things?

Speakers:

Alexander Then

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Alexander is a Veterinary Surgeon since 2015 with main interest in Diagnostic Imaging. He has undertaken Master Degree classes in CT, MRI, ultrasonography and nuclear medicine. These courses where a part of a program which is called Imaging and Functional Medicine and are mainly aimed for human doctors and radiology nurses. Further, he finished a 1.5 years long post graduate program for engineers that allows him to use the title of a 3D Printing Specialist. He has been doing 3D Printed jigs with the surgical planning at the 200+ employee Small Animal Hospital in Gothenburg, Sweden for over a year now and is keen to do even more. Recently he also started the first veterinary company in the Nordic countries which today is focused on offering guide systems with 3D printed jigs for veterinary professionals to make the surgical procedures easier and much more precise.

Andrew Allshorn

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Andrew Graduated Wolverhampton School of Art and Design with a Degree in Product Design. In 1994 he started his career in AM/3D Printing running an SLA250 and Vacuum system at Liverpool University, before being offered the position of Applications Engineer at 3D Systems introducing 3DPrinting all over the world. After nearly 30 years in the industry Andrew is still running his own company and is extremely passionate about promoting AM via STEAM Education and getting children involved at schools and colleges. Education is the way forward for this industry and it is also the AMUG philosophy for its members. He is a problem solver and love nothing more than helping develop new applications for all industries For the past three years Andrew has served in the Vice President position for AMUG and he also sits on the TCT Expert Advisory Board and is involved in their Bright Minds Initiative at the TCT3Sixty event, as well as being a Create Education Ambassador where he visits schools to educate children about our amazing industry.

Johnny Uday

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I am a Veterinarian Surgeon passionate about 3D printing; currently working designing and manufacturing patient specific implants for human/animal use.

Dr. Kalman Czeibert

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After graduation, he worked as a clinician veterinarian in a small animal hospital. In 2012, he joined the Department of Anatomy and Histology at the University of Veterinary Medicine, Budapest, to teach veterinary anatomy. In 2016, he became a research member of the Senior Family Dog Project at the ‘ELTE’ Eotvos Lorand University, which investigated canine cognitive dysfunction with an international ERC group. He defended his Ph.D. thesis on canine neuroanatomy and 3D modelling, and due to his interest in these topics, he coordinates the Canine Brain and Tissue Bank and regularly assists in small animal brain surgeries. Currently, he is working at LimesVet Ltd. in a research-innovation-development position to create custom-made veterinary equipment and integrating digital modelling, 3D printing and anatomical visualization into the routine clinical, research and educational life.

Moderator:

Richard Doerer

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Richard Doerer is the 3DHEALS Detroit Community Manager. He is the founder of Modl3D, LLC, a medical technology company specializing in 3D printing and medical imagery for veterinary practices and education. Recent projects include canine nasal sarcomas, brain meningiomas, and aneurysms in the caudal cava.

Richard made a career change to work in the medical field after hearing Dr. David Zopf at a Materialise event in Detroit. Dr. Zopf was a recent speaker at the 3DHEALS Detroit event at the University of Michigan in January 2020. 

A former Yale School of Architecture faculty member in architectural model building, Richard has been involved with 3D printing since the early 1990s with SLA’s from 3D Systems.

In addition to his work with Modl3D, Richard is the Additive Lab Manager/Engineering Manager for Adient, LLC. Adient, LLC is the largest global automotive seat manufacturer.  

Richard is an automotive industry expert featured on numerous panel discussions and holds numerous patents for innovative automotive applications. He is a graduate of Michigan State University, MBA and Yale School of Art, MFA.

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3D Printing for Cardiovascular System

The cardiovascular system indisputably dictates the fitness level and longevity of any individual. It is also one of the top killers and debilitating conditions of modern human beings no matter where you live. “Heart disease is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. One person dies every 36 seconds in the United States from cardiovascular disease. About 659,000 people in the United States die from heart disease each year—that’s 1 in every 4 deaths. Heart disease costs the United States about $363 billion each year from 2016 to 2017. This includes the cost of health care services, medicines, and lost productivity due to death.” [https://www.cdc.gov/heartdisease/facts.htm] But heart disease has many causes, one of which includes iatrogenic causes, a result of modern medicine. Cardiotoxicity is one of the major side effects of many cancer drugs, for example. Can 3D Bioprinting rejuvenate our hearts? To answer this question, we have invited one of the most comprehensive world-class experts from academia, industry, startup world to engage with the audiences on the possibilities of this emerging technology in solving a critical problem, topic including and not limited to bioprinting “mini-hearts”, “heart components”, “cardiac repair patch”, among others.

Speakers:

Vahid Serpooshan

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Vahid Serpooshan did his BSc and MSc in Materials Science and Engineering at Sharif University (Tehran, Iran, 1998-2003) and his Ph.D. in biomaterials and tissue engineering at McGill University (Montreal, Canada, 2007-2011). His Ph.D. thesis research focused on the design and optimization of scaffolding biomaterials for bone tissue engineering applications. Following his Ph.D., Dr. Serpooshan worked for 7 years at Stanford University School of Medicine as Postdoctoral Fellow (Pediatric Cardiology) and Instructor (Stanford Cardiovascular Institute). At Stanford, Dr. Serpooshan’s training and research were mainly centered on developing a new generation of engineered cardiac patch devices to repair damaged heart tissue following myocardial infarction (heart attack). The engineered patch was successfully tested in mouse and pig models and is now in preparation for clinical trials. He also worked on enabling technologies for human-machine hybrid cardiac tissue, using 3D bioprinting to assemble complex arrays of interfaces between synthetic and biological materials. In 2018, Dr. Vahid Serpooshan joined Emory University and Georgia Institute of Tech as Assistant Professor of Biomedical Engineering and Pediatrics, where his multidisciplinary team is now working on a variety of 3D bioprinting-based tissue engineering and disease modeling projects.

Asaf Toker

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Asaf is a pediatrician with years of experience in the biotechnology industry. For the last 3 years, Asaf is the CEO of Matricelf, an Israeli publicly-traded company in the area of tissue engineering and regenerative medicine.

Carmine Gentile

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Dr Carmine Gentile, PharmD/Ph.D., FAHA, received his BSc/MSc (Pharmaceutical Chemistry and Technologies) and PharmD at the University of Pisa, Italy, and his Ph.D. in Biomedical Sciences (Cardiovascular) at the Medical University of South Carolina, Charleston, SC, USA, funded by a prestigious American Heart Association Fellowship. Since 2013, Dr. Gentile has worked in Australia at the Heart Research Institute, the University of Sydney, and now at UTS, supported by several awards and grants, working within a multidisciplinary team with scientists, industry partners, and clinicians to quickly translate his findings from bench to bedside. He currently leads the Cardiovascular Regeneration Group (www.gentilelab.com), working on 3D bioprinting and stem cell technologies for cardiovascular tissue applications both at the Kolling Institute/University of Sydney and UTS. He is a Senior Lecturer (Honorary) within the Sydney Medical School (Northern) at the University of Sydney and a Senior Lecturer (Faculty) within the School of Biomedical Engineering (Faculty of Engineering and IT) at the University of Technology Sydney. 

Dr. Gentile is an internationally recognized expert in the field of 3D bioprinting and stem cell technologies and his more recent studies focus on novel molecular and cellular approaches to treat cardiovascular disease, including myocardial infarction and heart failure. These studies are based on the use of vascularized cardiac spheroids or “mini-hearts” he developed as “bio-inks” for human heart tissues. In 2016, he was invited as Visiting Research Fellow at Harvard Medical School, where he worked towards novel in-vitro models using mini-hearts to study human heart physiology.

Adam Feinberg

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Dr. Adam Feinberg is Co-Founder and CTO of FluidForm Inc, a start-up company commercializing FRESH 3D bioprinting technology, and a Professor at Carnegie Mellon University in the departments of Biomedical Engineering and Materials Science & Engineering. He earned his BS in Materials Science & Engineering from Cornell University in 1999 with Co-op experience at Abiomed, Inc., working on total artificial hearts. He then earned his Ph.D. in Biomedical Engineering from the University of Florida, focused on engineering cell-material interactions to prevent and enhance adhesion. This was followed by postdoctoral training at Harvard University, developing new biomaterials and stem cell-based cardiac tissue engineering strategies. Dr. Feinberg has co-authored over 50 peer-reviewed publications, holds over 20 US patents and patent applications, and has received multiple honors including the NSF CAREER Award, the NIH Director’s New Innovator Award, and Fellow of the American Institute for Medical and Biological Engineering. A primary research focus is engineering extracellular matrix (ECM) protein scaffolds using advanced biomanufacturing and 3D bioprinting approaches for multiple applications including cancer models, regenerative scaffolds, skeletal muscle, and cardiac muscle tissue engineering. At FluidForm, he is driving the commercialization of the FRESH 3D bioprinting platform for a wide range of applications in the biopharma, medical device, and regenerative medicine industries.

Moderator:

William Harley

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William is a Ph.D. candidate within the School of Biomedical Engineering at the University of Melbourne. He obtained a Certificate 3 in Business Management and an Honors Degree in Medical Biotechnology from the University of New South Wales where he first entered research focusing on biomaterials, stem cells, and nanofabrication processes for tissue regeneration. Currently, his Ph.D. investigates the use of acoustic micromanipulation and 3D bioprinting as tools to pattern and define the cellular microenvironment. William has held roles as a research assistant and a business development consultant, where he currently serves as a Community and Events Manager for 3D Heals and an Organizing Committee Member for the Australian Bioprinting Workshop.

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3D Bioprinting Cancer

Cancer, what a modern-day existential threat to humanity, is a word that triggers a cringe from the most fearless. Over the past decades in modern medicine, we have made much progress in cancer care, ranging from diagnosis, surgical advancements, to therapeutics. Despite that, cancer is surpassing heart diseases as a leading cause of death in the United States in 2020. [Ref] The demand for faster diagnostics and better treatment is driving researchers to technologies like 3D printing and 3D bioprinting. 

Speakers:

Dr. Antti Arjonen

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Cancer research, microscopy, cell biology, image-based high-throughput screening, 3D bioprinting

Dr. Karolina Valente

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Karolina has a B.Sc. and M.Sc. in Chemical Engineering, and a Ph.D. in Mechanical Engineering. She has deep expertise in tissue engineering, 3D bioprinting, and oncology. Karolina has published multiple peer-reviewed papers and is currently an Assistant Teaching Professor at the University of Victoria and the CEO & CSO of VoxCell BioInnovation.

Raphael Lichtnecker

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I got my Master´s degree in Pharmaceutical Bioprocess Engineering at Technical University Munich. Afterwards I started as Business Development Manager at ViscoTec where I am responsible for the technology transfer of the progressive cavity pump to the bioprinting sector. I´m in this position for four years now.

Moderator:

Dr. Jenny Chen

jenny chen

Dr. Jenny Chen is trained as a neuroradiologist, founder/CEO of 3DHEALS. Her main interests include next generation education, 3D printing in the healthcare sector, automated biology, artificial intelligence. She is an angel investor who invests in Pitch3D companies.

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3D Printed Prosthetics

Over the years, the images of disabled children with colorful prosthetic limbs inspired impactful movements like the ENABLE community and Victoria Hand Project, as well as enumerable passionate innovators who have pushed the boundaries to increase accessibility and lower the cost of orthotics and prosthetics. However, the field of 3D printed prosthetics has advanced significantly since the days of ENABLE hands. These advancements include not just hardware, materials, but also software, designs, 3D scanning, and lately completely digitalized workflow at the point of care, often leveraging machine learning and artificial intelligence. More importantly, technologists are now working more closely with clinicians to create a more efficient and more evidence-based patient-centered clinical solution. In this highly anticipated webinar, we invited experts with decades of technical, business, and clinical experiences and diverse perspectives to give the attendees a 360-degree view of the current and future status of the industry. 

Speakers:

Bryan Craft

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Bryan Craft started his career in medical 3D technology during a time where Coronavirus was threatening the supply of critical medical equipment (PPE). Working with a service bureau in North Carolina, he and his team 3D printed and delivered thousands of face shields to medical professionals in North Carolina and beyond. Bryan has devoted his time to learn how the 3D technology industry can improve medical device manufacturing specifically for Orthotics and Prosthetics. In 2021, Bryan joined the medical technology company, Spentys, where he is making 3D technology a reality in O&P. His core focus is to enhance the patient experience by increasing customization, exploring advanced materials, and working closely with innovative clinicians. Bryan has investigated the time savings for clinicians who adopt streamlined 3D technology and continues to search for new applications and use cases.

Albert Shih

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Albert Shih is Professor in Mechanical Engineering, Biomedical Engineering, and Institute of Gerontology at the University of Michigan. He received PhD from Purdue University in 1991 and was a manufacturing engineer at Cummins and an Associate Professor at NC State University before joining the University of Michigan in 2003. He served in the Advanced Manufacturing National Program Office in 2017 and was the President of NAMRI SME in 2019-2020. Dr. Shih is a pioneer in biomedical manufacturing. He is the recipient of the Fulbright Scholar, SAE Teetor Educational Award, SME Taylor Research Medal and Education Award, and ASME Shaw Manufacturing Research, Blackall Machine Tool & Gage Award, and Ennor Manufacturing Technology Award. Professor Shih is the Fellow of ASME, SME, and CIRP.

Michael Peirone

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Michael started volunteering with Victoria Hand Project when it was still a university research project, and has seen it grow across the world. Through his years with VHP, Michael has gotten a broad view of the organization as a volunteer, student intern, Biomedical Designer, the COO, and most recently taking on the role of CEO.

Samer Moussa

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Samer Moussa has a background that merges design, clinical care, and business development of medical devices. With an undergrad in Mechanical Engineering, a Masters of Science in Orthotics and Prosthetics and currently pursuing an MBA, he has transitioned from everyday clinical care as a CPO to working as a product manager with different medical device manufacturers. From adjustable prosthetic sockets with LIM Innovations to innovative off-the-shelf knee and spine devices with Breg and the latest venture with HP, Arize Orthotics which is a fully developed end-to-end solution for custom orthotics. Samer has been in the O&P industry for 10 years and his main passion is finding the right bridge between new technology and clinical pain points in a way that both businesses can strive.

Prof. Dr. Hans-Werner Schmidt

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Hans-Werner Schmidt studied Chemistry at the University of Mainz (Germany) and ETH Zürich (Switzerland). He received his Dr. rer. nat. degree in Macromolecular Chemistry at the University of Mainz. After a stay at the DuPont Central Research in Wilmington, Delaware he moved to the University of Marburg to obtain his Habilitation. From 1989 to 1994 he was Assistant and Associate Professor of Materials with tenure at the Materials Department, College of Engineering at the University of California, Santa Barbara. Since 1994 he is Full Professor for Macromolecular Chemistry at the University of Bayreuth. He was Vice President for research at the University of Bayreuth and is founding director of the Bavarian Polymer Institute. He has many years of research experience in the development of polymer materials for emerging technologies. For over 10 years, he has been involved in the development of materials for additive manufacturing. As co-founder of the German based company PPprint, he is actively involved in the development of 3D printing materials for applications in medical technology.

Moderator:

Dr. Jenny Chen

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Dr. Jenny Chen is trained as a neuroradiologist, and founder/CEO of 3DHEALS. Her main interests include next-generation education, 3D printing in the healthcare sector, automated biology, and artificial intelligence. She is an angel investor who invests in Pitch3D companies.

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3D Printing in Hospitals

In recent years, many hospitals have started making a shift, from using medical images primarily for diagnostic purposes, to integrating them in patient-specific surgical planning. This has created enormous advantages for hospitals and their patients and is largely supported by the clarifying regulatory landscape, increased governmental support, new public and private initiatives, and the expanding role of the radiologist as an imaging expert. As part of this, an increasing number of hospitals across the world have integrated the practice of 3D printing into their medical care. Hospitals are recognizing the added value it brings to personalized patient care and the countless possibilities that are becoming a reality, in creating better treatment options.

Speakers:

Robert Hannan, MD

Director, CV Surgery Advanced Projects Laboratory | Medical Director, Quality, Nicklaus Children’s Health System | Cardiovascular Surgeon, Nicklaus Children’s Hospital

Robert Hannan, MD

Dr. Hannan holds multiple patents of medical devices, and developed Real Time Outcomes described above. His interests include delivery, measurement and transparency of quality medical care, advanced imaging, immersive technologies for patient care, and the use of innovation in clinical care and education.

Shafkat Anwar

Associate Professor of Pediatrics and Radiology, University of California San Francisco

Shafkat Anwar

Dr. Shafkat Anwar is a pediatric cardiologist at the University of California San Francisco. He specializes in non-invasive cardiac imaging, including echocardiography and cardiac magnetic resonance imaging (MRI). At UCSF, he is the Director of the Pediatric Heart Center’s Cardiac MRI and 3D+ Programs. He has founded two hospital-based 3D printing Centers – the first at Washington University in St. Louis, and currently he co-Directs UCSF’s Center for Advanced 3D+ Technologies (CA3D+). He is involved in several national and international collaborations related to 3D modeling and 3D printing. He is a founding member and the inaugural Chair of the Society for Cardiovascular Magnetic Resonance’s Advanced 3D+ Visualization Special Interest Group. Dr. Anwar completed his Residency in Pediatrics at Children’s National Medical Center, followed by a research fellowship at the National Institutes of Health. He completed his Pediatric Cardiology Fellowship at Cleveland Clinic, followed by Fellowship in Cardiac Imaging at Children’s Hospital of Philadelphia.

Muhanad Shraiteh

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Muhanad recently graduated with a master’s in bioengineering and a bachelor’s in mechanical engineering. He joined the Cardiovascular Surgery Advanced Projects Lab last year and is working on innovative design and development ideas that have an impact on people’s lives and improve standards of care.. Muhanad’s research interests and past projects include topics such as biomechanics and global health engineering.

Imre J. Barabás

Imre J. Barabás

Imre is the leader of the Semmelweis 3D Centre (SE3D) at the most prestigious Semmelweis University in Budapest, Hungary. Imre works as a cardiac surgeon at Semmelweis University while running the center. His Ph.D. topic was a patient-specific 3D printed exoskeleton for left ventricle assist device implantation. Imre has gained experience during the development and licensing of the exoskeleton under the medical device regulation. Imre is the CEO and Founder of the 3D Guide Ltd. using the exoskeleton patent. The SE3D is a facility for 3D printing technology at Semmelweis University based on the three pillars of the university: patient care, education, and research. My mission is to promote 3D printing technology and build community among those clinicians using 3D technology at the university. The capability of 3D technology is a personalized and safer decision-making tool in clinicians’ hands. Imre has introduced a new undergraduate course called Basics of Digital Medicine in 2021. My goal is to give practical knowledge to medical students about 3D technology. The curriculum covers the full spectrum of medical 3D technology, including data capture, DICOM data transformation, segmentation, 3D printing, and post-processing printed objects. 3D printing is still relatively new learning and teaching tool for medical education. Patient-specific models with anatomical fidelity made from imaging datasets can significantly improve a new generation of surgeons’ knowledge and skills. The SE3D Centre offers a cooperation platform between researchers and clinicians under my leadership. My vision is to find new ways to address old and new medical issues through frontier experiments.

Kerim Genc

Kerim Genc

Kerim Genc is the Business Development Manager for the Simpleware Product Group at Synopsys. He joined Simpleware in 2011 and is currently responsible for managing global sales, business development, partnerships and technical marketing content development, with a significant focus on image-based patient specific workflows for 3D Printing and surgical guides/planning. He received his BS and MS in biomechanics from the University of Calgary and the Pennsylvania State University respectively, and completed his PhD in Biomedical Engineering at Case Western Reserve University, examining countermeasures to and computational models of spaceflight induced bone loss and fracture risk.

Thomas Haglund

Thomas Haglund

Thomas’ graduate studies were in cardiac tissue engineering before joining the team at Nicklaus Children’s. Thomas has been instrumental in operationalizing 3D printing and Mixed Reality at the Nicklaus Children’s Hospital since 2018. With the help of generous donors, the CVS APL has touched the lives of hundreds of children and their family.

Dr. Stephen Ryan

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Dr. Stephen Ryan is a practicing physician and co-founder of PolyUnity Tech. He has explored Additive Manufacturing applications in healthcare for over 6 years as a researcher and entrepreneur. He has been involved in the creation of many 3D Printed products including medical simulations, patient specific medical devices, PPE and end use hospital equipment. His current role is to build relationships with hospital stakeholders to better understand regulatory considerations and advocate for the adoption of additive manufacturing services within the healthcare ecosystem.

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Bioprinting Vasculatures

3D bioprinting vasculatures is perhaps the holy grail of the next industrial revolution in healthcare. Biofabrication and bioprinting of any viable three-dimensional tissue will not be successful unless the vascularization challenge has been solved. Many organizations and talents around the world are actively tackling this challenge, but where are we exactly? Hear the latest perspectives, updates, and revelations from a group of technical and industrial superstars. 

Speakers:

Taci Pereira

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Taci Pereira is Vice President and General Manager, Bioprinting at 3D Systems, where she leads the development and commercialization of research tools for 3D bioprinting applications. Taci was previously the Chief Scientific Officer at Allevi, a startup 3D Systems acquired in 2021. Taci leads the 3D bioprinting working group for the Regenerative Medicine Manufacturing Society, a professional society dedicated to advancing manufacturing solutions for the field of regenerative medicine. Originally from Curitiba, Brazil , She holds a Bachelor of Science in Bioengineering from Harvard University, where she worked at the Wyss Institute for Biologically Inspired Engineering. Taci’s research at the Mooney Laboratory for Cell and Tissue Engineering (Wyss) focused on biomaterials for cancer immunotherapy, under the advisory of David Mooney, Ph.D.

Ibrahim T. Ozbolat

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Ibrahim Tarik Ozbolat is an Associate Professor of Engineering Science and Mechanics, Biomedical Engineering and Neurosurgery, and a member of the Huck Institutes of the Life Sciences at Penn State University. Dr. Ozbolat’s main area of research is in the field of 3D Bioprinting. He has been working on several aspects of bioprinting such as bioprinting processes, bioink materials, bioprinters and post-bioprinting tissue maturation for manufacturing of more than a dozen tissues and organs. Dr. Ozbolat is a leading scientist with over 150 publications, including a sole-authored book in his domain. Due to his notable contributions to the field of bioprinting, he has received several prestigious international and national awards including 2014 NSF CAREER Award, 2014 SME Outstanding Young Manufacturing Engineer Award, 2014 ASME Chao and Trigger Young Manufacturing Engineer Award, 2014 ASME Tau Pi Sigma Gold Medal, 2015 IIE Dr. Hamid K. Eldin Outstanding Early Career Industrial Engineer in Academia Award, 2015 International Outstanding Young Researcher in Freeform and Additive Manufacturing Award and 2017 Hartz Family Career Development Professorship at Penn State.

Marc Thurner

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Marc Thurner is a visionary, entrepreneur and pioneer in biofabrication technologies, currently acting as Chief Executive Officer at mimiX biotherapeutics Ltd. He pioneered the field of 3D bioprinting with his former creation regenHU Ltd, today recognized as an industry leader in the development of innovative biomedical solutions. A micro technology engineer Graduate, Marc started his professional career as an R&D engineer, managing international projects for the high precision automation industry. His avant-gardiste view that the future of regenerative medicine lay in converging engineering and biomedical science, brought him to found regenHU Ltd in 2007 and mimiX biotherapeutics Ltd in 2020. In 2012 Marc created the regenHU spin-off Vivos Dental Ltd, specialized in innovative 3D-printed bone grafting solutions for oral bone augmentation. Being an industry transformation leader, mimiX biotherapeutics develops leading-edge solutions in biotechnology and tissue engineering that enable scientific and clinical breakthroughs. The Swiss-based company collaborates with a global network of scientific innovators and industry players and leads the development of biomedical products for regenerative medicine and drug discovery. Marc Thurner and the mimiX biotherapeutics team are passionate about addressing the current and next generation biotechnology challenges to help the progress of Life Sciences.

Pierre-Alexandre LAURENT, PhD

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During my PhD, I worked on the role of PI3Ks on the platelet functions and thrombus formation using in particular microfluidic/videomicroscopy technics. My postdoc research was focused on the development of 3D bone marrow models for the study of thrombocytopenia, developping bioreactor for ex-vivo platelet production and drug testing purposes using silk fibroin biomaterial and 3D bioprinting approach. I am now Senior Field Application Scientist at CELLINK, a BICO company promoting how our amazing bioconvergence technologies contribute to the future of biomedical research.

Moderator:

William Harley

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William is a Ph.D. candidate within the School of Biomedical Engineering at the University of Melbourne. He obtained a certificate 3 in business management and an honors degree in medical biotechnology from the University of New South Wales where he first entered research focusing on biomaterials, stem cells, and nanofabrication processes for tissue regeneration. Currently, his Ph.D. investigates the use of acoustic micromanipulation and 3D bioprinting as tools to pattern and define the cellular microenvironment. William has held roles as a research assistant and a business development consultant, where he currently serves as a community and events manager for 3D Heals and an organizing committee member for the Australian Bioprinting Workshop.

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3D Microfabrication: Medical Applications

What is microfabrication? Based on the latest definition, microfabrication is “a collection of technologies which are utilized in making microdevices.” As the name implies, 3D microfabrication is the manufacturing technique using layering of materials to produce a 3D structure at a typical scale of micrometer or even nanometer dimension. In other words, 3D printing at micro or nanometer scale. One commonly known 3D microfabrication or additive manufacturing microdevice process that can achieve this level of resolution includes 3D laser microfabrication such as laser direct-writing (LDW). Microfluidic devices are often produced using LDW. Microstereolithography, another common technique based on stereolithography principles fabricates 3D components by repeatedly layering photopolymerizable resin and curing under an ultraviolet laser. Finally, multiphoton lithography (e.g. two photopolymerizations) is another recognized 3D microfabrication process that can 3D printing sub-micrometer resolution). Over the past several years, there is an increasing interest in the space with a handful of new startups more visible in the spotlight in the 3D printing space. One of the driving forces is the enormous need to mass manufacture complex but small (if not smaller) medical devices. Examples include stents, microneedles, endoscopic components, and many others that are facing size challenges. Another driving force is the potential point of care of these devices meeting the design and manufacturing demand without facing external competition, trade secret loss, and supply chain crisis.

Speakers:

John Kawola

CEO of Boston Micro Fabrication

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John is the CEO of Boston Micro Fabrication (BMF) an additive manufacturing technology company with a focus on high resolution, accuracy, and precision. From 2016 to 2019, John served as President-Americas for Ultimaker, the leading open-source desktop 3D printing company. From 2012 to 2016, John was the CEO of Harvest Automation. Harvest developed and deployed an autonomous mobile robotic platform that assists workers with difficult, repetitive material handling. John was VP of Sales and then CEO of Z Corporation from 1997 until 2012. Z Corporation led the way in introducing fast, easy to use and full-color 3D printing into a wide range of industries. John is also currently the Chairman of Labminds, a laboratory automation technology company, and a Board Director at Industrial ML, an industrial machine learning company. John received a BS in Mechanical Engineering from Cornell University, MS in Mechanical Engineering from Rensselaer, and an MBA from Union College.

Adam Steege

Adam Steege

After completing undergraduate work in Math, Physics, and Mechanical Engineering, Adam started his first company, Agile EndoSurgery. Agile developed novel articulated laparoscopic surgical devices, using a wide variety of fabrication techniques. Through this development process, as well as through his consulting work that resulted in the development of 3 other commercialized medical devices, Adam learned the potential and the shortcomings of 3d printing in medtech. With over 80 pending and issued patents, and 10 years of medical device development in addition to automation, robotics, and manufacturing expertise, Adam founded Trio Labs to solve the problems of precision and scalability in metal additive manufacturing.

Martin Hermatschweiler

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Martin is CEO of Nanoscribe, the pioneer and market leader in high-precision additive manufacturing. Various, application-specific products underpin the expertise for specialized manufacturing scenarios such as prototyping, mastering, alignment with nanoprecision, and bioprinting. Nanoscribe is a spin-off of the Karlsruhe Institute of Technology (KIT) and belongs to the BICO Group since June 2021. With Nanoscribe, the BICO Group is the world’s first life science company with internal Two-Photon Polymerization (2PP) additive manufacturing capabilities. Martin is co-founder and managing partner of Nanoscribe, ever since the company was founded in 2007. The scientific expertise of the graduate physicist lies in laser patterning of polymers as well as in their casting into high refractive index optical materials. In 2015, he has been listed among the TOP 40 entrepreneurs within Germany younger than 40 years by the journal “Capital”, the so-called “young elite”.

Albert Folch

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Albert Folch’s lab works at the interface between 3D-printing, microfluidics and cancer. He received both his BSc (1989) and PhD (1994) in Physics from the University of Barcelona (UB), Spain, in 1989. During his Ph.D. he was a visiting scientist from 1990–91 at the Lawrence Berkeley Lab working on AFM under Dr. Miquel Salmeron. From 1994–1996, he was a postdoc at MIT developing MEMS under Martin Schmidt (EECS) and Mark Wrighton (Chemistry). In 1997, he joined Mehmet Toner’s lab as a postdoc at Harvard-MGH to apply soft lithography to tissue engineering. He has been at Seattle’s UW BioE since June 2000, where he is now a full Professor, accumulating over 11,000 citations. In 20 years, he has supervised 18 postdocs (17% of whom have reached faculty rank), 12 Ph.D. students (25% faculty rank), 15 M.S. students, and >40 undergraduates. In 2001 he received an NSF Career Award, in 2006 a NASA Space Act Award, and in 2014 he was elected to the AIMBE College of Fellows (Class of 2015). He has served on the Advisory Board of Lab on a Chip between 2006-2017 and on the Editorial Board of Micromachines since 2019. He is the sole author of 5 books, including “Introduction to BioMEMS” (2012, Taylor&Francis), a textbook adopted by ~100 departments in 18 countries, and “Hidden in Plain Sight: The History, Science, and Engineering of Microfluidic Technology” (MIT Press, to appear in April 2022). Since 2007, the lab runs a celebrated outreach art program called BAIT (Bringing Art Into Technology), which has produced seven exhibits, a popular resource gallery of >2,000 free images related to microfluidics and microfabrication, and a YouTube channel that plays microfluidic videos with music which accumulates ~157,000 visits since 2009.

Abstract: 

The miniaturization of biomedical assays is of paramount importance for expanding healthcare access, for reducing healthcare costs, and for expediting biological research. However, biologists and clinicians typically do not have access to microfluidic technology because they do not have the engineering expertise or equipment required to fabricate and/or operate microfluidic devices. Furthermore, the present commercialization path for microfluidic devices is usually restricted to high-volume applications in order to recover the large investment needed to develop the plastic molding processes. We are developing microfluidic devices through stereolithography, a high-resolution form of 3D printing, in order to make microfluidic technology readily available via the web to biomedical scientists. Most available SL resins do not have all the favorable physicochemical properties of the above-named plastics (e.g., biocompatibility, transparency, elasticity, and gas permeability), so the performance of SL-printed devices is still inferior to that of equivalent PDMS devices. Inspired by the success of hydrogel PEG-DA biocompatibility, we have developed microfluidic devices by SL in resins that share all the advantageous attributes of PDMS and thermoplastics so that we can 3D-print designs with comparable performance and biocompatibility to those that are presently molded.

Moderator:

Dr. Jenny Chen

jenny chen

Dr. Jenny Chen is trained as a neuroradiologist, founder/CEO of 3DHEALS. Her main interests include next generation education, 3D printing in the healthcare sector, automated biology, artificial intelligence. She is an angel investor who invests in Pitch3D companies.

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3D Bioprinting and Organoids

From 3D cell cultures, organoids, spheroids, to 3D bioprinted organoids, a lot of these concepts aren’t exactly explained accurately in the popular media, despite the fact that 3D tissue cultures are more than a decade old. In a recent Nature article, an organoid was defined as “a 3D multicellular in vitro tissue construct (using stem cells) that
mimics its corresponding in vivo organ, such that it can be used to study aspects of that organ in the tissue culture dish.” However, such a construct is not without problems. Challenges of reproducibility, lack of complexity, and lack of vasculatures and immune cells are preventing this method to be fully and widely adopted to the applications organoids promised to accomplish. 3D printing or the 3D bioprinting method appears to offer solutions in the next generation of organoids and 3D tissue culture.

Speakers:

Stephanie Willerth

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Dr. Willerth, a Full Professor in Biomedical Engineering, holds a Canada Research Chair in Biomedical Engineering at the University of Victoria where she has dual appointments in the Department of Mechanical Engineering and the Division of Medical Sciences. She also holds an appointment with the School of Biomedical Engineering at the University of British Columbia. She recently founded the start-up company – Axolotl Biosciences that sells high quality bioinks for bioprinting human tissue models. She is an active member of the steering committee of the B.C. Regenerative Medicine Initiative and the Stem Cell Network. She also serves as a staff scientist at Creative Destruction Lab. She served as the Acting Director of the Centre for Biomedical Research and the Biomedical Engineering undergraduate program at the University of Victoria from 2018-2021 and as the President of Canadian Biomaterials Society from 2018-2019.

Tania Hübscher

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Tania Hübscher is a PhD student in the Laboratory of Stem Cell Bioengineering, at the Swiss Federal Institute of Technology (EPFL). She holds a Bachelor in Biology from the University of Neuchatel and a Master in Life Sciences from EPFL. She conducted her Master thesis at Stanford University. During that time, she became fascinated by stem cells and their potential and decided to pursue this research as a PhD. In Prof. Lutolf lab, we are mostly working with organoids, and bioengineering approaches towards the next generation of organoid cultures.

Y. Shrike Zhang

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Dr. Zhang’s research interests include 3D bioprinting, organ-on-a-chip, biomaterials, regenerative engineering, and bioanalysis. He is an author of >265 peer-reviewed publications with citations of ~20,000 and h-index of 70. His scientific contributions have been recognized by over 40 regional, national and international awards.

Dr. Jenny Chen

jenny chen

Dr. Jenny Chen is trained as a neuroradiologist, founder/CEO of 3DHEALS. Her main interests include next generation education, 3D printing in the healthcare sector, automated biology, artificial intelligence. She is an angel investor who invests in Pitch3D companies.

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3D Printing for Performance Sports

What does performance sports have anything to do with healthcare? A lot. In fact, the relationship is very much reciprocal. Many innovations in performance sports, which aim to protect, augment, and optimize athletes, can translate to benefit patients in the much more regulated healthcare industry. For example, in the space of sports medicine and rehabilitation. On other hand, medical devices aim to monitor, improve sports performance, and speed up recovery after an injury can be scaled up to benefit a larger active population. The design and technical capabilities of 3D printing are adding new possibilities for us to not just better snowboards, helmets, shoes, and much more ways we can enjoy our games, but also provide insights into how we can improve patients’ lives. In this virtual event, we brought together founders, entrepreneurs, scientists, and technologists to have a fun conversation on the current status of 3D printing in performance sports. 

Speakers:

Emili S. Taixés

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Emili S. Taixés is the CEO and co-founder of Athos, the first 3D printed and customized climbing shoe ever. Following his passion for innovation, technology and sports, Emili and his team are defining the new rules of the industry based on products with better fit with the user and the planet. Mass customization and on-demand production are some examples of the opportunities that 3D printing technology brings to the table to design a better world.

Luis Baldez

Luis Baldez

Luis Baldez is one of the pioneers of the 3D printing in HP, having led early customer research and technology development starting in 2009. After the successful launch of the first HP Multi Jet Fusion product in 2016, he helped create the market and business development organization to accelerate customer adoption of HP’s 3D printing technologies. His current responsibilities include strategic account management, solution development and partner engagements for Footwear, Healthcare and Industrial customers. Luis is also the Executive Director of the 3MF Consortium, an industry consortium focused on data standards to improve cross-platform interoperability. Luis has a background in electrical and software engineering and held several engineering and management positions in HP, Synopsys, and a couple of startups across the globe. He holds a MSc degree of Electronics Engineering from University of Brasilia, Brazil and an Innovation Leadership education from Stanford University Graduate School of Business. He is currently based at the HP office in Vancouver, Washington.

Annika Norden

Annika Norden

Annika is an engineer, designer, and creator, excited by any opportunity that brings these facets together. As a Sr. Solutions Engineer at nTopology, Annika collaborates with customers throughout medical, consumer, and automotive industries, helping innovate everyday.

Moderator:

Dr. Jenny Chen

jenny chen

Dr. Jenny Chen is trained as a neuroradiologist, founder/CEO of 3DHEALS. Her main interests include next generation education, 3D printing in the healthcare sector, automated biology, artificial intelligence. She is an angel investor who invests in Pitch3D companies.